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JCST

Journal of Current Science and Technology

ISSN 2630-0656 (Online)

Preparation and properties of poly(butylene succinate) porous scaffold by fused deposition modeling and salt leaching techniques

  • Kasidis Teerasuchai, Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University, Sanamchandra Palace Campus, Nakhon Pathom 73000, Thailand
  • Bussarin Ksapabutr, Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University, Sanamchandra Palace Campus, Nakhon Pathom 73000, Thailand
  • Manop Panapoy, Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University, Sanamchandra Palace Campus, Nakhon Pathom 73000, Thailand
  • Nattawut Chaiyut, Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University, Sanamchandra Palace Campus, Nakhon Pathom 73000, Thailand, Corresponding author: E-mail: chaiyut_n@su.ac.th

Abstract

Scaffolds are a promising innovation that create a suitable environment for the restoration of tissues.  They can also be used to achieve efficient drug delivery to specific sites.  Poly(butylene succinate) (PBS) is a biocompatible and biodegradable polymer that has been utilized in various research fields.  Fused deposition modeling (FDM) was conducted to construct PBS scaffolds with two specific lay-down patterns: grid and triangle.  The salt leaching technique was also used to produce pores in the scaffolds.  A morphological study, porosity measurement, and contact angle analysis were carried out to characterize scaffold morphology, pore characteristics and surface properties.  Salt content and type of lay-down patterns were found to affect the porosity and wettability of the scaffolds.  Porosity increased with an increasing proportion of salt while scaffolds with a triangle pattern were more porous than grid pattern at the same salt content.  The wettability test showed that the contact angle of all scaffolds ranged between 88° and 102°, while the grid pattern was more hydrophobic than the triangle pattern.

Keywords: fused deposition modeling, poly(butylene succinate), porosity, porous scaffold, salt leaching, wettability

PDF (1.45 MB)

DOI: 10.14456/jcst.2021.33

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Approved By TCI (2020 - 2024)

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